Glythera

Glythera Ltd is a biotechnology company specializing in the development of platform technologies for next generation biotherapeutics with 2 core programmes:- PermaLink™ - a novel, stable, highly cysteine-specific conjugation platform for antibody drug conjugates (ADCs). PermaLink™ is associated with enhanced anti-tumour activity in vivo vs maleimide in comparative ADC models. It is suitable for cleavable and non-cleavable systems - PermaCarb™ - a novel sialylation correction platform which can (i) improve bioavailability & enhance product performance and (ii) remove the issue of sialic acid contamination. It is particularly appropriate for the development of biobetters and biosimilars. PermaCarb™ has been validated vs several biotherapeutics, including FSH and etanercept. Based in the NE of England, Glythera has dedicated bioprocessing and chemistry laboratories enabling us to conduct in-house evaluations for our partners to progress applications of PermaLink™ and PermaCarb™ technologies. We are seeking license collaborations for PermaLink™ and out-license partners for PermaCarb™.

Website:
www.glythera.com
Organisation type
Dr David Simpson
Chief Executive Officer